I got scolded by the vet NOT to use desitin cause there's is zinc. I never had issues using it on my other dogs......but I figured for this time I won't use it as she gave me special wipes ( buy it online!!!! Vet is expensive! !!) And drops. She said to use polysporin before we go to antibiotics if she needs it. From what I see right now Nyala doesn't need antibiotics. Think polysporin is working. Mind you it's an irritation she and not a yeast infection. Thank god!