First thing...to clear up those nasty sore wrinkles...NOTHING works as well as Pinxav. It "stains" so use it sparingly...But it will clear up any rash fast.
[Learned this when my SIL had a baby and we were vacationing at the ocean...diaper rash + ocean water = raw tushie Pinxav is what was recommended and it cleared up almost over night]
So I've used this on my Tank's wrinkles as well...Just again use it sparingly...and be careful around the eyes.
ALSO...Benadryl...ALLERGY ONLY...What does your dog weigh? 1 pill is 25 mg...so you would give that do a dog that weighs 25 lbs... And go from there...a dog 50 lbs would take two. It maybe an allergy related thing...
But food also can cause issues...believe it or not. I did read others ask you what you were feeding. I switched my food with my bulldogs and was AMAZED at how little I now need to clean their wrinkles...Tank used to have sore and puffy wrinkles at times...and now...NEVER! So that is another area you may want to venture into figuring out.
But definitely once you clean those wrinkles dry them really good.