Make sure there isn't an ulcer when you are applying the steroid eye drop. They can happen quickly...the ulcers, just from the eyelashes. IF there is an ulcer....applying a steroid drop to the eye will exacerbate it. Orion has 1 eye lash that caused an ulcer. We went to one clinic and got a clean bill of health...the next day I went to another and they said she did indeed have an eye ulcer. Clinic one prescribed Neo/poly/dex...... Clinic 2 immediately took her off it and put her on Neo/poly/gent.