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Thread: Mila is sick again, REALLY high white blood cell count

  1. #13
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    Default Re: Mila is sick again, REALLY high white blood cell count

    Praying for you and Mila. Hope she gets better soon!

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    Default Re: Mila is sick again, REALLY high white blood cell count

    I'm no help either, and the only person I can think of that may have a suggestion would be @Twice I just wanted to send hugs and bully kisses for a speedy recovery

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    Default Re: Mila is sick again, REALLY high white blood cell count

    Hope all is okay with your baby! Hugs and prayers your way.
    Karen & Frankie

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    Default Re: Mila is sick again, REALLY high white blood cell count

    Quote Originally Posted by gobronco View Post
    Mila is sick again. She keeps getting sick, this is the third time in a few months. Her left eye starts to roll back into Her head (may just be the covering moving up). This is followed by her losing her energy just laying on the couch with her eyes open. We have to feed her crushed ice to keep her hydrated. She is normally our crazy little white dog (AKA flying squirrel). She just spent 3 weeks on high doses of steroids and 5 weeks on a heavy dose of antibiotics. Her white blood cell count is currently 24,000. 15,000 is considered really high. Has anyone else come across these symptoms? She has already spent time in the hospital. And went through over $2,000 worth of testing. Blood tests, X-rays, ultrasounds, tests for tick born diseases and autoimmune diseases. Everything the vet could think of. Any ideas?

    I've been trying to get to this post all day!! Sorry

    The CBC all comes in normal except for the high WBC? Normally that signifies some kind of infection but after 5 weeks of antibiotics that is doubtful. I assume the blood was taken AFTER the 3 weeks of steroids? The steroids alone can cause the body to create more white blood cells. If the test was taken immediately after or during the steroid treatment, wait a week and request a mini panel. (the mini panel is cheaper and only tests a couple of things)

    There are other things that can cause this high of a value. Inflammation. Adrenal glands. Stress. You said that is he dehydrated and that is a definite cause of his high WBC. Ask your vet about subQ fluids for a few days to rehydrate him.

    You don't say why the doctor put him on steroids in the first place?
    Do you have copies of his test results?

    For me, her name was Abby
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    Default Re: Mila is sick again, REALLY high white blood cell count

    I'm praying for you guys... Hopefully you will figure out what's going on soon!!!

    "What we once enjoyed and deeply loved, we can never lose, for all that we love deeply becomes a part of us." Helen Keller
    RIP Wellie, Bella, Winston & Roxie

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    Default Re: Mila is sick again, REALLY high white blood cell count

    I hate to say, the last time I had a dog with really high WBC had serious case of cancer. Praying for good news on Mila's recovery soon
    Life is like a box of chocolate covered

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    Default Re: Mila is sick again, REALLY high white blood cell count

    Something in the original post hasnt sat right with me all day. I couldnt put my finger on it until just a few minutes ago. @gobronco you said that her doctor told you that 15000 is "really high"? That's not true. The normal range (depending on your lab) can be anywhere from 6000 to 17000. 24,000 is high no doubt but not nearly high enough to panic over just yet. Not if that is the ONLY abnormal thing in the blood panel. An increase of 5k could absolutely be caused by dehydration alone.

    I went into what I call "the Abby Archives" and dug up an article for you...

    The long-term pattern of prednisone-induced leukocytosis was examined in 80 patients. Our results disclosed an extremely variable leukocytic responses, in which the white blood cell count surpassed 20,000/mm3 as early as the first day of treatment, an increase that persisted for the duration of therapy. Although the degree of leukocytosis was related to the dosage administered, it did appear sooner with higher doses. Leukocytosis reached maximal values within two weeks in most cases, after which the white blood cell count decreased, albeit not to pretreatment levels. The leukocytosis was attributed predominantly to a rise in the polymorphonuclear white blood cells, a phenomenon that coincided with monocytosis, eosinopenia and a variable degree of lymphopenia. It can be concluded that even small doses of prednisone, administered over a prolonged period of time, can induce extreme and persistent leukocytosis.


    stop the steroids and retest
    Last edited by Twice; 08-27-2013 at 09:27 PM.

    For me, her name was Abby
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    Default Re: Mila is sick again, REALLY high white blood cell count

    Quote Originally Posted by Twice View Post
    Something in the original post hasnt sat right with me all day. I couldnt put my finger on it until just a few minutes ago. @gobronco you said that her doctor told you that 15000 is "really high"? That's not true. The normal range (depending on your lab) can be anywhere from 6000 to 17000. 24,000 is high no doubt but not nearly high enough to panic over just yet. Not if that is the ONLY abnormal thing in the blood panel. An increase of 5k could absolutely be caused by dehydration alone.

    I went into what I call "the Abby Archives" and dug up an article for you...

    The long-term pattern of prednisone-induced leukocytosis was examined in 80 patients. Our results disclosed an extremely variable leukocytic responses, in which the white blood cell count surpassed 20,000/mm3 as early as the first day of treatment, an increase that persisted for the duration of therapy. Although the degree of leukocytosis was related to the dosage administered, it did appear sooner with higher doses. Leukocytosis reached maximal values within two weeks in most cases, after which the white blood cell count decreased, albeit not to pretreatment levels. The leukocytosis was attributed predominantly to a rise in the polymorphonuclear white blood cells, a phenomenon that coincided with monocytosis, eosinopenia and a variable degree of lymphopenia. It can be concluded that even small doses of prednisone, administered over a prolonged period of time, can induce extreme and persistent leukocytosis. stop the steroids and retest
    I hope you know what a blessing you are~how lucky we are you're with us.

    Much admiration for your hard work & effort to go back to school and learn
    so much in order to help us help our bullies and your selfless work for rescuing.

    All this and more, going thru personal hardship, Bev, you are a inspiration to me
    and all you meet. Praying for the Heavens to open and flood you with all you need
    & your dreams to come true. Sending much love, dear one. GOD always bless you!


    My 1st bully, Brutus
    RIP beloved boy.

  9. #21
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    Default Re: Mila is sick again, REALLY high white blood cell count

    When she got sick, in July, (second time) they put her on steroids and antibiotics because she was going down quick. They ran all of the tests before they started her on steroids and antibiotics. Her white blood cell counts were high but i don't know what they were. It took her 2-3 weeks to get back to normal (flying squirrel). She got sick again about 3 weeks after stopping the steroids and 1-1/2 weeks after stopping the antibotics. The high latest white blood cell counts were after 1-1/2 days of steroids. By that time she was all amped up and starting to feel better. We finally got her in to see her normal vet, same clinic. He says no more steroids if she gets sick again he wants to see her sick. He has always been a very good vet. At about 70 years old he has the experience. The way he sits on the floor and feels the dogs is always reassuring. Btw the local bulldog breeders all know him but don't care for him much because he says their dogs are fat. At the moment she is feeling better and back to her crazy little white dog self. Much quicker recovery than last time she got sick.

  10. #22
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    Default Re: Mila is sick again, REALLY high white blood cell count

    Quote Originally Posted by Texas Carol View Post
    I hope you know what a blessing you are~how lucky we are you're with us.

    Much admiration for your hard work & effort to go back to school and learn
    so much in order to help us help our bullies and your selfless work for rescuing.

    All this and more, going thru personal hardship, Bev, you are a inspiration to me
    and all you meet. Praying for the Heavens to open and flood you with all you need
    & your dreams to come true. Sending much love, dear one. GOD always bless you!
    I'm not a saint lol I learned all that I know now because of Abby and my mission to "save her". Silly I know since there was no way possible to save her. Sometimes I think the only reason I keep going, keep studying is to find the one thing that I didn't do that would have saved her. She is gone 10 months and she still motivates me and every day I apologize to her for failing her.

    Quote Originally Posted by gobronco View Post
    When she got sick, in July, (second time) they put her on steroids and antibiotics because she was going down quick. They ran all of the tests before they started her on steroids and antibiotics. Her white blood cell counts were high but i don't know what they were. It took her 2-3 weeks to get back to normal (flying squirrel). She got sick again about 3 weeks after stopping the steroids and 1-1/2 weeks after stopping the antibotics. The high latest white blood cell counts were after 1-1/2 days of steroids. By that time she was all amped up and starting to feel better. We finally got her in to see her normal vet, same clinic. He says no more steroids if she gets sick again he wants to see her sick. He has always been a very good vet. At about 70 years old he has the experience. The way he sits on the floor and feels the dogs is always reassuring. Btw the local bulldog breeders all know him but don't care for him much because he says their dogs are fat. At the moment she is feeling better and back to her crazy little white dog self. Much quicker recovery than last time she got sick.
    I'm glad she is feeling better. I pray it's a forever condition

    Have you gotten a second opinion? Maybe it's time to speak to some of those breeders to find out what vet they use. Or, better yet, find a veterinary internist. There is a Dr Hamilton about 20 minutes from San Jose who gets great reviews on Yelp. If (God forbid) she gets sick again, ask your current vet for copies of all her test results and bring those with you so that you don't have to retest.

    For me, her name was Abby
    10/24/2011 - 11/23/1012


    Obtaining a dog license should require more than writing a check.

  11. #23
    Bully lov'in wonder from down under Become a 4 Paw Member
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    Default Re: Mila is sick again, REALLY high white blood cell count

    I am sending prayers for you and Mila that you find an answer real soon and she recovers

  12. #24
    Pet Sitter gobronco's Avatar
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    Default Re: Mila is sick again, REALLY high white blood cell count

    She has now seen two different doctors. The first one seemed like he knew what he was doing. They tested her for everything. Our main vet hasn't seen her when she was really showing symptoms. He did mention seeing a specialist (internist) if she gets sick again and he can't figure it out. Crossing our fingers that she doesn't get sick again. Hopefully if she gets sick again it will be when he is on call. He has been able to figure out tough issues, in the past, that other vets were not sure what to do or just wanted to do unneeded surgeries Etc.

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