- Mar 21, 2011
- 13,407
- 848
- Country
- USA
- Bulldog(s) Names
- BeBe, Hazel, Lucy Lu, JLO, Hillary, Henri, & Katie
My Lucy Lu used to get them until I switched her food and no more problem. That was over a year ago.
Inter-digital Cysts. . . .
- Thread starter Maximus
- Start date
Gunny has suffered with these its called deep pyoderma its caused by a bacteria I tried all the soaks and all the antibotics the only thing that helped my gunny was clindamycin I have a study that was done with dogs with deep popyoderma (interdital cysts) I will paste it here hope it helps. they are so painful it just breaks your heart.
Twenty dogs were examined for staphylococcal deep
pyoderma at the Cornell University College of Veterinary
Medicine (Table 1). The dogs ranged from 4 mo to 11 y
of age, represented numerous breeds and a mongrel,
and consisted of 14 males and 6 females. Weights
ranged from 11 to 61 kg. Duration of clinical signs
ranged from 2 wk to 4 y. Thirteen dogs had received
prior antibiotic therapy and had recurrent infections. All
dogs had deep pyoderma involving the paws, pressure
points, face, or large areas of the body surface. Eight dogs
had previously diagnosed concurrent dermatoses
(Table 2) that may have been predisposing factors for the
development of deep pyoderma. The other 12 dogs had
no identifiable predisposing cause. Skin scrapings and
microscopic examination of pus from skin lesions were
performed on all dogs. Cytological examination of
pus expressed from draining tracts revealed pyogranulomatous inflammation, wherein the majority of neutrophils were degenerate and many contained phagocytosed cocci. Exudate collected from intact nodules and
plaques on all dogs was submitted for bacterial culture
and antibiotic susceptibility testing.
To be admitted into the study, all dogs had to have a
positive culture for S. intermedius that was tested for
in vitro susceptibility to clindamycin. In vitro susceptibility to clindamycin was determined by the broth
microdilution system, as recommended by the National
Committee for Clinical Laboratory Standards (28). All
plates were commercially prepared and tested by using
the Radiometer Sensitive system (Sensititre Microbiology
Systems, Radiometer America, Westlake, Ohio, USA).
In addition, informed consent had to have been obtained
from the dogs' owners. Clindamycin capsules (75 mg and
150 mg) were administered PO at 11 mg/kg BW, q24h.
Treatment with clindamycin was initiated at the time the
dogs were discharged from the clinic, before the results
of culture and in vitro antibiotic susceptibility testing
were known. Treatment was continued until all active
lesions had disappeared and then for another 7 d (1,29-31).
In 13 dogs, response to therapy was assessed by reexaminations at the College of Veterinary Medicine. In
7 dogs, response to therapy was assessed by reexaminations at the referring veterinarians' clinics and their
subsequent telephone conversations with one of the
authors. Reexaminations were performed every 2 to 3 wk.
The post-treatment follow-up period was 3 mo for all
dogs.
Results
Staphylococcus intermedius was isolated in pure culture
from all 20 dogs. Eighteen (90%) of the 20 isolates
were susceptible to clindamycin in vitro. The other 2 isolates were of intermediate susceptibility (case 16) or
resistant (case 3).
Twenty dogs were treated with clindamycin, and all
20 had excellent responses (complete resolution of their
infections). Treatment periods ranged from 21 to 91 d,
with an average of 45 d. Five dogs (25%) suffered recurrences within the 3-month posttreatment follow-up
period (Table 2). There did not appear to be any influence
of age, sex, duration of disease, concurrent dermatosis
(Table 2), or previous antibiotic therapy on the response
to clindamycin therapy. One dog (case 2) vomited when
the clindamycin was given on an empty stomach, but not
when it was administered with food.
Discussion
Clindamycin produced an excellent result in 100% of
the dogs treated, which compares very favorably with
results reported with other antibiotics used to treat
deep staphylococcal pyoderma in dogs: enrofloxacin (29),
ormetoprim-sulfadimethoxine (30), tylosin (31),
754 Can Vet J Volume 39, December 1998
754 Can Vot J Volume 39, December 1998Table 2. Therapeutical data on 20 dogs with staphylococ
Twenty dogs were examined for staphylococcal deep
pyoderma at the Cornell University College of Veterinary
Medicine (Table 1). The dogs ranged from 4 mo to 11 y
of age, represented numerous breeds and a mongrel,
and consisted of 14 males and 6 females. Weights
ranged from 11 to 61 kg. Duration of clinical signs
ranged from 2 wk to 4 y. Thirteen dogs had received
prior antibiotic therapy and had recurrent infections. All
dogs had deep pyoderma involving the paws, pressure
points, face, or large areas of the body surface. Eight dogs
had previously diagnosed concurrent dermatoses
(Table 2) that may have been predisposing factors for the
development of deep pyoderma. The other 12 dogs had
no identifiable predisposing cause. Skin scrapings and
microscopic examination of pus from skin lesions were
performed on all dogs. Cytological examination of
pus expressed from draining tracts revealed pyogranulomatous inflammation, wherein the majority of neutrophils were degenerate and many contained phagocytosed cocci. Exudate collected from intact nodules and
plaques on all dogs was submitted for bacterial culture
and antibiotic susceptibility testing.
To be admitted into the study, all dogs had to have a
positive culture for S. intermedius that was tested for
in vitro susceptibility to clindamycin. In vitro susceptibility to clindamycin was determined by the broth
microdilution system, as recommended by the National
Committee for Clinical Laboratory Standards (28). All
plates were commercially prepared and tested by using
the Radiometer Sensitive system (Sensititre Microbiology
Systems, Radiometer America, Westlake, Ohio, USA).
In addition, informed consent had to have been obtained
from the dogs' owners. Clindamycin capsules (75 mg and
150 mg) were administered PO at 11 mg/kg BW, q24h.
Treatment with clindamycin was initiated at the time the
dogs were discharged from the clinic, before the results
of culture and in vitro antibiotic susceptibility testing
were known. Treatment was continued until all active
lesions had disappeared and then for another 7 d (1,29-31).
In 13 dogs, response to therapy was assessed by reexaminations at the College of Veterinary Medicine. In
7 dogs, response to therapy was assessed by reexaminations at the referring veterinarians' clinics and their
subsequent telephone conversations with one of the
authors. Reexaminations were performed every 2 to 3 wk.
The post-treatment follow-up period was 3 mo for all
dogs.
Results
Staphylococcus intermedius was isolated in pure culture
from all 20 dogs. Eighteen (90%) of the 20 isolates
were susceptible to clindamycin in vitro. The other 2 isolates were of intermediate susceptibility (case 16) or
resistant (case 3).
Twenty dogs were treated with clindamycin, and all
20 had excellent responses (complete resolution of their
infections). Treatment periods ranged from 21 to 91 d,
with an average of 45 d. Five dogs (25%) suffered recurrences within the 3-month posttreatment follow-up
period (Table 2). There did not appear to be any influence
of age, sex, duration of disease, concurrent dermatosis
(Table 2), or previous antibiotic therapy on the response
to clindamycin therapy. One dog (case 2) vomited when
the clindamycin was given on an empty stomach, but not
when it was administered with food.
Discussion
Clindamycin produced an excellent result in 100% of
the dogs treated, which compares very favorably with
results reported with other antibiotics used to treat
deep staphylococcal pyoderma in dogs: enrofloxacin (29),
ormetoprim-sulfadimethoxine (30), tylosin (31),
754 Can Vet J Volume 39, December 1998
754 Can Vot J Volume 39, December 1998Table 2. Therapeutical data on 20 dogs with staphylococ
OP
- Thread Starter
- Thread starter
- #48
Hi again,
I had to pull up my original post and re-read the entire thread. Maximus' interdigital cysts remain. Today they are red and swollen and appear irritated. He has been on ATOPICA, steroids, antibiotics. He has had complete Allergy testing and it came back negative for just about everything. His face wrinkles are also red, raw and irritated, despite powders, creams, ointments and antibiotics. The one problem area that I see is CHICKEN. Although he does not get Chicken dog food, he does get cooked chicken, and that might be the problem. So I'm going to have to eliminate Chicken from his diet, and see if there is an improvement. I will retry the Zyrtec
and look for the Ketoconazole/Chlorhexidine shampoo to soak his paws in, along with the Epsom salts.
I'll keep you posted.
Thanks.
~ Patrick
I had to pull up my original post and re-read the entire thread. Maximus' interdigital cysts remain. Today they are red and swollen and appear irritated. He has been on ATOPICA, steroids, antibiotics. He has had complete Allergy testing and it came back negative for just about everything. His face wrinkles are also red, raw and irritated, despite powders, creams, ointments and antibiotics. The one problem area that I see is CHICKEN. Although he does not get Chicken dog food, he does get cooked chicken, and that might be the problem. So I'm going to have to eliminate Chicken from his diet, and see if there is an improvement. I will retry the Zyrtec
and look for the Ketoconazole/Chlorhexidine shampoo to soak his paws in, along with the Epsom salts.
I'll keep you posted.
Thanks.
~ Patrick
ironically Duke had these a few years back... he is on a regimen now to keep things at bay but just tonight we found a small one starting.. I really thing this allergy season is the worst . do you think it could be outside things as well? and I totally agree about the chicken. Duke did NOT test that he was allergic to chicken but every time we feed it we have issues.. God Bless you ..I just feel terrible for you both.
What has worked for us ( after hundreds of dollars in meds and trying allergy shots etc ) he takes 10 mg of prednisone every other day and TWO Zryrtec ( our dermatologist told us it is twice the adult dose) he also told us in bad allergy seasons to give the Zyrter every day.. Is Max on any of this now?? I will look for my post about another member who went through this as well... Hang in there
What has worked for us ( after hundreds of dollars in meds and trying allergy shots etc ) he takes 10 mg of prednisone every other day and TWO Zryrtec ( our dermatologist told us it is twice the adult dose) he also told us in bad allergy seasons to give the Zyrter every day.. Is Max on any of this now?? I will look for my post about another member who went through this as well... Hang in there
@JAKEISGREAT this is the name of the thread I was trying to share for @Maximus but not sure how to share the link
Re: NEED ALLERGY HELP! Don't know what to do....
http://www.englishbulldognews.com/forums/showthread.php?t=14923
Hopefully this works [MENTION=2091]BabyDuke[/MENTION]. :D
http://www.englishbulldognews.com/forums/showthread.php?t=14923
Hopefully this works [MENTION=2091]BabyDuke[/MENTION]. :D
Last edited by a moderator:
OP
- Thread Starter
- Thread starter
- #51
Hi -
Max just finished a course of steroids and antibiotics. He has not been outside in awhile - he can't handle anything over 70-degrees. I will restart him on Zyrtec and eliminate the Chicken (and give him lamb).
Max just finished a course of steroids and antibiotics. He has not been outside in awhile - he can't handle anything over 70-degrees. I will restart him on Zyrtec and eliminate the Chicken (and give him lamb).
JAKEISGREAT
.................
[MENTION=701]Maximus[/MENTION]..I got the link [MENTION=2091]BabyDuke[/MENTION] wanted you to see!
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