Hi, Petee was diagnosed with Demodetic Mange mites at about 2 1/5 months of age. It was moderate. I took the least toxic approach from my Vet. She put him on Pyoban Shampoo and Gel- Alternating the two. Also, Cephalexin antibiotic and benadryl. I was already changing his food from Eukanuba puppy to a high quality food- Natures Variety Grain Free food. You need to boost Coco's immune system. The mites suppresses the immune system. If you haven't already, change to a high quality food-slowly- so as not to stress Coco's system even more. Also, adding a fish oil helps too. I used Nutri-Vet Wild Alaskan Salmon Oil and gave it every night on his food. I got a lot of this advice from the great members here! Within 2 months time, he was clear! He had three skin scrapings and was negative. His is now almost 8 months old and looks great. You can't even tell where the spots were. Some people used Ivermectin, Milbemycin oxime (Interceptor), or even Amitraz dips. I did not want to take that toxic route on a 2 1/5 month old puppy unless i had too. Lucky for us and Petee, the safer route worked. I did try the Goodwinol ointment and shampoo but it ended up burning his skin and the ointment was greasy and reddish in color on his white fur (he looked worse then what he was) so i went back to Pyoban. I was diligent with it-and tried to be patient! There is a lot of info. online. I am now in the process of changing his food to Fromm Beef Fratata and Veg. because he was very gassy, loose stools, and bad tear stains on the other food-every dog is different, and like the members will tell you, it will take time to find the right food for your bully. Best of luck to you and Coco!