We take Winston everywhere with us basically from 5 minute rides to 8 hours! He is great in the car and loves looking out the window at all the cars going by. The only advice I have is to make sure to bring some chew toys for the ride to keep them occupied and some wipes to wipe those little paws after they take a potty break! You never know what they can pick up at a rest stop. Good luck, I hope you have a great vacation!