Hi Ted, no I haven't heard of any of the supplements you have listed. We give our guys a high quality food, we feed Fromm's Lamb and Lentil, or Fromm's Beef FrFrittata, and we add 2 Tbsp. of yogurt to their morning kibble for the Probiotics, it aids in digestion, and boosts the immune system, we add 1 Tbsp of apple cider vinegar to their drinking water everyday, ACV is a natural anti- inflammatory, it kills the bad bacteria in the body, so boosts the immune system, and it also balances the Ph levels of the blood, there are many other benefits of ACV, you can go to the Home Page and read the article. We add 1 Tbsp of coconut oil for the Omega 3 Fatty Acids, this is good for the skin, coat and brain, and we also add 1 tsp. Kelp, kelp has very vitamin and mineral that your dog will need.